What is Lupus Nephritis?

Lupus nephritis is a
serious complication of lupus

Lupus nephritis may be more common than you think

Lupus nephritis is an inflammation of the kidneys caused by lupus. If left untreated it can lead to significant health problems, permanent kidney damage, and even kidney failure. About 1 out of 2 people with lupus develop lupus nephritis over time. Compared to non-Hispanic White people, disease prevalence is roughly:

4 times higher for people of African and Asian descent

2 times higher for Hispanic and Native peoples


Common signs and symptoms of lupus nephritis are:

Swelling (often in the feet, ankles, or legs)

Foamy or frothy urine

Blood in the urine (called hematuria)

Protein in the urine (called proteinuria)

Symptoms can be subtle or inconsistent and often overlap with other diseases, so your doctor should also monitor you for signs of lupus nephritis with routine urine and blood tests.

Routine urine testing looks for protein in the urine, which can help your doctor catch lupus nephritis early and start to determine a treatment plan.

Stand up to lupus nephritis

The goal of lupus nephritis treatment is to help stop the attack on the kidneys and help protect them from further permanent damage. Until recently, there were no FDA-approved treatments specifically for lupus nephritis.

Building a treatment plan around LUPKYNIS from the very beginning can raise the bar for how lupus nephritis is treated.